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What Is Epimedium Extract (Icariin)? Applications, Dosage, Alternatives & Specifications

Last updated: 2026-11-14 · CAS 489-32-7 · Food Grade

Quick facts
Name
Epimedium Extract (Icariin)
CAS number
489-32-7
Grade
Food Grade
Certifications
ISO 9001 · ISO 22000 · HACCP · FAMI-QS · Kosher · Halal · GMP · SGS
Application areas
4
Documentation
COA · TDS · SDS

Overview

Epimedium Extract, also known as Horny Goat Weed Extract, is a natural plant extract processed from the dried aerial parts of plants of the Epimedium genus (Berberidaceae family) through extraction, filtration, concentration, and drying processes. It is a functional ingredient with multiple biological activities. Epimedium was first recorded in the Shennong Bencao Jing (The Divine Farmer‘s Materia Medica) as a medium-grade herb. It has a long medicinal history as a traditional Chinese tonic herb, with functions of tonifying kidney yang, strengthening bones and tendons, and dispelling wind-dampness. It is used for impotence, seminal emission, weak bones and muscles, rheumatic pain, numbness and contracture, and menopausal hypertension. The main active components of Epimedium extract are flavonoids, including icariin, epimedin A, epimedin B, and epimedin C. The Chinese Pharmacopoeia (2020 edition) uses the total content of epimedin A, epimedin B, epimedin C, and icariin as the quality control standard. Epimedium contains flavonoids, polysaccharides, alkaloids, lignans, trace elements, etc., with pharmacological activities including anti-inflammatory, antioxidant, anti-osteoporosis, anti-tumor, and anti-apoptotic effects. Epimedium extract products are available in various forms, including standardized extract powders (icariin content ranging from 1% to 98%), ratio extracts, total flavonoid extracts, compound preparations, and capsules/tablets.

The main active components of Epimedium extract are shown in the table below: Component Category

Epimedium extract is known as “herbal Viagra” and the “king of kidney tonification and yang enhancement,” occupying a leading position in the natural men‘s health plant extract market. Its most prominent core advantages include: classic kidney tonification and yang enhancement effects, vasodilation and erectile function improvement, bone health protection (anti-osteoporosis), immune regulation and anti-aging functions, long traditional medicinal history, and extensive modern scientific research support.

Applications

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Dietary Supplements

Dietary supplements are the largest end-use market for Epimedium extract. 1 Men’s Health and Sexual Function Products: Epimedium extract is a core…

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Health Foods

Epimedium extract can be applied in various health foods: 1 Bone Health Products: Epimedium extract has anti-osteoporosis effects and can increase…

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Sports Nutrition Products

Epimedium extract is increasingly widely used in the sports nutrition market: 1 Testosterone Support Products: Icariin supports healthy testosterone…

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Pharmaceutical Adjuvant Products

Adjuvant Therapy for Osteoporosis: Epimedium extract (such as Xianling Gubao Capsules) has been used as an adjuvant therapy for osteoporosis in…

Specification

Icariin ContentTest MethodMain Characteristics
Typical Applications
Low Grade (Standard)1% – 5%HPLC
Brown-yellow powder, retains multiple flavonoids, cost-effectiveGeneral health foods, compound formulations
Medium Grade10% – 20%HPLC
Brown-yellow to brown powder, moderate icariin contentDietary supplements, sports nutrition
High Grade40% – 60%HPLC
Brown powder, high purity icariinPremium health foods, capsule filling, exports
Ultra-High Purity Grade≥98%HPLC
Light yellow crystalline powder, monomer series, extremely high purityPharmaceutical products, chemical reference substances, research, premium exports
Total Flavonoids GradeTotal flavonoids ≥20%–40%UV/HPLC
Mixture retaining multiple flavonoid componentsHealth foods, traditional Chinese medicine compound prescriptions
Ratio Extract4:1, 10:1, 20:1—
Retains multiple active componentsHealth foods, traditional Chinese medicine compound prescriptions
Organic GradeCustomized per customer requirementsHPLC
USDA/EU organic certified, non-GMO, non-irradiatedPremium organic dietary supplements
Liquid GradeCalculated by solid contentHPLC
Concentrated solution, convenient for formulationLiquid supplements, drops
3.3 Typical Technical Specifications (Supplier Specifications)ParameterSpecification Range/Index
Test Method
AppearanceBrown-yellow to brown powder, uniform in colorVisual inspection
Icariin Content (HPLC), %1%, 5%, 10%, 20%, 40%, 60%, 98% (depending on grade)GB/T 22247/HPLC method
Total Content of Epimedin A+B+C+Icariin, %According to Chinese Pharmacopoeia standard (for crude drug)HPLC method
Particle Size (powder form)80 mesh – 120 meshSieving method
Loss on Drying (Moisture), %≤5.0% – 8.0%GB 5009.3
Ash, %≤8.0%GB 5009.4
Total Arsenic (As), mg/kg≤1.0GB 5009.11
Lead (Pb), mg/kg≤1.0GB 5009.12
Cadmium (Cd), mg/kg≤0.5GB 5009.15
Mercury (Hg), mg/kg≤0.1GB 5009.17
Heavy Metals (as Pb), mg/kg≤10GB 5009.74
Pesticide ResiduesCompliant with export target country standardsGC-MS/LC-MS/MS
Solvent ResiduesCompliant with relevant standards—
Total Plate Count, CFU/g≤1000GB 4789.2
Mold and Yeast, CFU/g≤100GB 4789.15
Coliforms, MPN/g≤30GB 4789.3
Salmonella (25g)Not detectedGB 4789.4
Staphylococcus aureus (25g)Not detectedGB 4789.10
Packaging Specifications1 kg/bag, 5 kg/bag, 10 kg/bag, 20 kg/drum, 25 kg/drum
Shelf Life24 months (sealed, protected from light, stored in a cool dry place)
3.4 Packaging and Storage

Packaging & Storage

  • Packing: 25kg net fiber drum with double PE liner.
  • Sample: 100-500g free sample available.
  • Storage: Keep in tightly closed packaging, cool, dry, well-ventilated. Protect from light and moisture.
  • Shelf Life: 24 months from production date.

Quality & Certifications

ISO 9001 ISO 22000 HACCP FAMI-QS Kosher Halal GMP SGS

Every batch tested by in-house QC lab. COA, TDS, SDS provided with each shipment.

Regulatory & Compliance

EU

Complies with EU regulations and FAMI-QS standards.

USA

Meets FDA and AAFCO requirements.

China

Registered under Chinese MOA regulations.

International

Kosher, Halal, ISO certified. FTA forms available.

Safety & Handling

  • Hazard Class: Generally non-hazardous. Refer to SDS for details.
  • Storage: Room temperature, dry, sealed. Avoid strong oxidizers.
  • Transport: Non-dangerous goods. Standard sea/air freight.
  • SDS: Available on request at sales@xadditive.cn.

Frequently asked questions

MOQ?

MOQ is 1kg for trial, 25kg for regular orders. Free samples available.

Shelf life?

24 months from production date when stored properly.

Certifications?

ISO 9001, ISO 22000, HACCP, FAMI-QS, Kosher, Halal, COA, SDS, TDS.

How to get quote?

Email sales@xadditive.cn with your requirement. Reply within 30 minutes.

Request a quote & COA

Ask for the current specification sheet, a COA sample and a bulk quotation — reply within 30 minutes on working days.

sales@xadditive.cn Full product page & pricing