What Is Epimedium Extract (Icariin)? Applications, Dosage, Alternatives & Specifications
Last updated: 2026-11-14 · CAS 489-32-7 · Food Grade
- Quick facts
- Name
- Epimedium Extract (Icariin)
- CAS number
- 489-32-7
- Grade
- Food Grade
- Certifications
- ISO 9001 · ISO 22000 · HACCP · FAMI-QS · Kosher · Halal · GMP · SGS
- Application areas
- 4
- Documentation
- COA · TDS · SDS
Overview
Epimedium Extract, also known as Horny Goat Weed Extract, is a natural plant extract processed from the dried aerial parts of plants of the Epimedium genus (Berberidaceae family) through extraction, filtration, concentration, and drying processes. It is a functional ingredient with multiple biological activities. Epimedium was first recorded in the Shennong Bencao Jing (The Divine Farmer‘s Materia Medica) as a medium-grade herb. It has a long medicinal history as a traditional Chinese tonic herb, with functions of tonifying kidney yang, strengthening bones and tendons, and dispelling wind-dampness. It is used for impotence, seminal emission, weak bones and muscles, rheumatic pain, numbness and contracture, and menopausal hypertension. The main active components of Epimedium extract are flavonoids, including icariin, epimedin A, epimedin B, and epimedin C. The Chinese Pharmacopoeia (2020 edition) uses the total content of epimedin A, epimedin B, epimedin C, and icariin as the quality control standard. Epimedium contains flavonoids, polysaccharides, alkaloids, lignans, trace elements, etc., with pharmacological activities including anti-inflammatory, antioxidant, anti-osteoporosis, anti-tumor, and anti-apoptotic effects. Epimedium extract products are available in various forms, including standardized extract powders (icariin content ranging from 1% to 98%), ratio extracts, total flavonoid extracts, compound preparations, and capsules/tablets.
The main active components of Epimedium extract are shown in the table below: Component Category
Epimedium extract is known as “herbal Viagra” and the “king of kidney tonification and yang enhancement,” occupying a leading position in the natural men‘s health plant extract market. Its most prominent core advantages include: classic kidney tonification and yang enhancement effects, vasodilation and erectile function improvement, bone health protection (anti-osteoporosis), immune regulation and anti-aging functions, long traditional medicinal history, and extensive modern scientific research support.
Applications
Dietary Supplements
Dietary supplements are the largest end-use market for Epimedium extract. 1 Men’s Health and Sexual Function Products: Epimedium extract is a core…
Health Foods
Epimedium extract can be applied in various health foods: 1 Bone Health Products: Epimedium extract has anti-osteoporosis effects and can increase…
Sports Nutrition Products
Epimedium extract is increasingly widely used in the sports nutrition market: 1 Testosterone Support Products: Icariin supports healthy testosterone…
Pharmaceutical Adjuvant Products
Adjuvant Therapy for Osteoporosis: Epimedium extract (such as Xianling Gubao Capsules) has been used as an adjuvant therapy for osteoporosis in…
Specification
| Icariin Content | Test Method | Main Characteristics |
|---|---|---|
| Typical Applications | ||
| Low Grade (Standard) | 1% – 5% | HPLC |
| Brown-yellow powder, retains multiple flavonoids, cost-effective | General health foods, compound formulations | |
| Medium Grade | 10% – 20% | HPLC |
| Brown-yellow to brown powder, moderate icariin content | Dietary supplements, sports nutrition | |
| High Grade | 40% – 60% | HPLC |
| Brown powder, high purity icariin | Premium health foods, capsule filling, exports | |
| Ultra-High Purity Grade | ≥98% | HPLC |
| Light yellow crystalline powder, monomer series, extremely high purity | Pharmaceutical products, chemical reference substances, research, premium exports | |
| Total Flavonoids Grade | Total flavonoids ≥20%–40% | UV/HPLC |
| Mixture retaining multiple flavonoid components | Health foods, traditional Chinese medicine compound prescriptions | |
| Ratio Extract | 4:1, 10:1, 20:1 | — |
| Retains multiple active components | Health foods, traditional Chinese medicine compound prescriptions | |
| Organic Grade | Customized per customer requirements | HPLC |
| USDA/EU organic certified, non-GMO, non-irradiated | Premium organic dietary supplements | |
| Liquid Grade | Calculated by solid content | HPLC |
| Concentrated solution, convenient for formulation | Liquid supplements, drops | |
| 3.3 Typical Technical Specifications (Supplier Specifications) | Parameter | Specification Range/Index |
| Test Method | ||
| Appearance | Brown-yellow to brown powder, uniform in color | Visual inspection |
| Icariin Content (HPLC), % | 1%, 5%, 10%, 20%, 40%, 60%, 98% (depending on grade) | GB/T 22247/HPLC method |
| Total Content of Epimedin A+B+C+Icariin, % | According to Chinese Pharmacopoeia standard (for crude drug) | HPLC method |
| Particle Size (powder form) | 80 mesh – 120 mesh | Sieving method |
| Loss on Drying (Moisture), % | ≤5.0% – 8.0% | GB 5009.3 |
| Ash, % | ≤8.0% | GB 5009.4 |
| Total Arsenic (As), mg/kg | ≤1.0 | GB 5009.11 |
| Lead (Pb), mg/kg | ≤1.0 | GB 5009.12 |
| Cadmium (Cd), mg/kg | ≤0.5 | GB 5009.15 |
| Mercury (Hg), mg/kg | ≤0.1 | GB 5009.17 |
| Heavy Metals (as Pb), mg/kg | ≤10 | GB 5009.74 |
| Pesticide Residues | Compliant with export target country standards | GC-MS/LC-MS/MS |
| Solvent Residues | Compliant with relevant standards | — |
| Total Plate Count, CFU/g | ≤1000 | GB 4789.2 |
| Mold and Yeast, CFU/g | ≤100 | GB 4789.15 |
| Coliforms, MPN/g | ≤30 | GB 4789.3 |
| Salmonella (25g) | Not detected | GB 4789.4 |
| Staphylococcus aureus (25g) | Not detected | GB 4789.10 |
| Packaging Specifications | 1 kg/bag, 5 kg/bag, 10 kg/bag, 20 kg/drum, 25 kg/drum | |
| Shelf Life | 24 months (sealed, protected from light, stored in a cool dry place) | |
| 3.4 Packaging and Storage |
Packaging & Storage
- Packing: 25kg net fiber drum with double PE liner.
- Sample: 100-500g free sample available.
- Storage: Keep in tightly closed packaging, cool, dry, well-ventilated. Protect from light and moisture.
- Shelf Life: 24 months from production date.
Quality & Certifications
Every batch tested by in-house QC lab. COA, TDS, SDS provided with each shipment.
Regulatory & Compliance
EU
Complies with EU regulations and FAMI-QS standards.
USA
Meets FDA and AAFCO requirements.
China
Registered under Chinese MOA regulations.
International
Kosher, Halal, ISO certified. FTA forms available.
Safety & Handling
- Hazard Class: Generally non-hazardous. Refer to SDS for details.
- Storage: Room temperature, dry, sealed. Avoid strong oxidizers.
- Transport: Non-dangerous goods. Standard sea/air freight.
- SDS: Available on request at sales@xadditive.cn.
Frequently asked questions
MOQ?
MOQ is 1kg for trial, 25kg for regular orders. Free samples available.
Shelf life?
24 months from production date when stored properly.
Certifications?
ISO 9001, ISO 22000, HACCP, FAMI-QS, Kosher, Halal, COA, SDS, TDS.
How to get quote?
Email sales@xadditive.cn with your requirement. Reply within 30 minutes.
Request a quote & COA
Ask for the current specification sheet, a COA sample and a bulk quotation — reply within 30 minutes on working days.
