¿Qué es 3-Nitrooxypropanol (3-NOP), Ruminant Methane-Reducing Pienso Additive? Aplicaciones, dosis, alternativas y especificaciones

3-Nitrooxypropanol (3-NOP), con el chemical formula HO-CH2-CH2-O-NO2 and CAS number 100502–66–7, es un colorless transparent aceitey líquido at temperatura ambiente. It is insoluble en agua and readily soluble en carbon tetrachloride, ethanol, acetonitrile, y otros orgánico solvents. 3-NOP es un mononitrate ester of 1,3-propanediol and belongs to a class of methyl-coenzima M reductase (MCR) inhibitors. 3-NOP es un chemically synthesized small-molecule orgánico compound that, when used as a feed additive, specifically targets methanogenic archaea in the rumen of ruminants, inhibiting the final catalytic step of methanogenesis. Its core mechanism of action is: the nitrooxy ester group in the 3-NOP molecule selectively binds to methyl-coenzima M reductase and inactivates the enzima by temporarily oxidizing the nickel ion from +1 to +2 at the active site. Because 3-NOP es un structural analog of methyl-coenzima M, it can bind with coenzima B, thereby reducing the binding of methyl-coenzima M with coenzima B to form methane. 3-NOP is the world's first feed additive specifically for enteric methane mitigation in ruminants to receive approval in major markets, con el trade name Bovaer® (developed by DSM-Firmenich). El producto ofrece farmers a low daily cost and has been proven in approved countries to effectively reducen enteric methane emissions without compromising animal performance.

3-NOP products can be divided into the following main varieties by content specification and formulation: Series

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