¿Qué es Milk Thistle Extract (Silymarin/Silybin)? Aplicaciones, dosis, alternativas y especificaciones

Milk Thistle, with botanical name Silybum marianum (L.) Gaertn., es una annual or biennial herb belonging to the Asteraceae family. Milk Thistle Extract (also known as Silymarin) es un natural plant extracto produced from the dried ripe fruits of Silybum marianum through extractoion, purification, and drying processes. El principal active component is Silymarin, which appears as a yellow or brown-yellow polvo or cristalline polvo con una bitter taste. Silymarin has been used to treat hepatobiliary diseases for over 2,000 years. In ancient Greece and Roman times, Milk Thistle was already used to treat liver and gallbladder disorders. Modern research shows that Silymarin se reconoce como one of the most effective flavonoids for liver diseases discovered to date, earning the title of "natural hepatoprotegenive agent". Silymarin refers to a flavonolignan compound extractoed from the seed coat of Silybum marianum, a medicinal plant of the Asteraceae family [10†L5-L6]. Silymarin exhibits multiple pharmacological activities and se utiliza ampliamente in pharmaceuticals, health foods, foods, and cosmetics.

El núcleo active component of Milk Thistle Extract is Silymarin, a flavonolignan compound complex primarily consisting of four isomers: Silybin (also called Silibinin), Isosilybin, Silychristin, and Silydianin. Silybin is the most abundant and biologically active component in Silymarin, typically accounting for 50% to 70% of total Silymarin content. Active Component

(3) Promotion of Hepatocyte Regeneration and Repair: Silymarin accelerates DNA synthesis in liver cells and promueve protein synthesis, facilitating the production of new hepatocytes or the repair of already damaged ones. Clinical studies have demonstrated that Silybin stabilizes the hepatocyte membrane, mantiene its integrity, promueve the restoration of hepatocellular ultrastructure, mejora the division and growth of normal hepatocytes, and aumenta the synthesis of RNA and proteins in hepatocytes.