Qu'est-ce que Epsilon-Polylysine (Natural Preservative), Feed/ ? Applications, dosage, alternatives et spécifications

ε-Polylysine, English name is ε-Polylysine, also known as ε-PL, est un naturel cationic polypeptide produced by microbial fermentation, generally composed of 25 to 35 L-lysine residues connected by amide bonds formed through the α-carboxyl group and the ε-amino group, and is the only naturelly occurring homopolymeric amino acid with antibacterial properties. It has broad application value in the global food, pharmaceutical, cosmetic, and feed industries. Its molecular formula is H[C6H12N2O]n•H2O (n=25–35), molecular weight is typically between 3500 and 5000, and CAS number is 28211–04–3. As an emerging naturel biological conservateur, ε-polylysine has rapidly gained prominence in the sécurité alimentaire sector and est reconnu comme a green, highly effective product that effectively replaces traditional chemical conservateurs. In terms of chemical structure, ε-polylysine belongs to the category of polycationic polypeptides, rich in positive charges. This unique cationic property allows it to electrostatically adsorb to the surface of negatively charged microbial cell membranes, destroying membrane integrity through physical disruption, causing leakage of microbial cell contents and subsequent cell death. This physical disruption mechanism gives ε-polylysine an extremely broad antibacterial spectrum and hardly induces microbial resistance. ε-Polylysine typically appears as a white to light yellow poudre, is highly hygroscopic, and has a slight bitter taste. Its metabolic product in the human body is L-lysine, which can be completely digested and absorbed by the human body, making it safe and non-toxic.

ε-Polylysine est reconnu comme a star molecule among naturel green conservateurs, occupying a rapidly rising core position in the global industrie alimentaire and biotechnology fields. Its most outstanding advantages lie in its excellent broad-spectrum antibacterial activity, outstanding thermal stability, safety surpassing traditional conservateurs, unique multi-target antibacterial mechanism, and the nutritional value from its hydrolysis products. 1 Broad-Spectrum and Élevély Effective Antibacterial Activity: ε-Polylysine exhibits excellent inhibitory effects against gramme-positive bacteria, gramme-negative bacteria, yeasts, and molds. It is particularly effective against gramme-negative bacteria such as Escherichia coli and Salmonella, which are difficult to inhibit with chemical conservateurs. It also inhibits heat-resistant Bacillus spores and some viruses. Its antibacterial spectrum is the broadest among all naturel food conservateurs. 2 Excellent Thermal Stabilité: ε-Polylysine remains stable even after heating at 120°C for 20 minutes, withstanding food thermal processing such as UHT ultra-high-temperature instantaneous sterilization and high-pressure sterilization. Thest unllows it to be flexibly incorporated throughout the entire thermal processing of products, maintaining its antibacterial effect whether added before, during, or after processing. 3 Élevé Sécurité and Nutritional Properties: ε-Polylysine can be broken down in the human body into L-lysine, one of the eight essential amino acids for the human body. It est un nutritional antibacterial agent with safety far exceeding that of chemical conservateurs. Its acute oral toxicity is 5g/kg, classifying it as practically non-toxic. It has been approved as a additif alimentaire in multiple countries including Japon, the États-Unis, South Corée, and Chine. 4 Unique Physical Mechanism of Action: Carrying a large number of positive charges, ε-polylysine electrostatically adsorbs to the negatively charged cell membranes of microorganisms, causing microbial cell death through physical disruption. This non-specific mechanism does not rely on specific biochemical targets and hardly induces microbial resistance. This est un significant advantage that traditional antibiotics and chemical conservateurs cannot match. 5 Wide pH Adaptability: Within the broad range of pH 3 to 9, ε-polylysine maintient strong antibacterial activity. Whether in acidic products (such as beverages and jams) or neutral products (such as rice and meat products), it exerts stable conservateur effects. 6 Synergistic Enhancement: When used in combination with biologique acids, glycine, alcohol, fatty acid glycerides, and other substances, ε-polylysine exhibits significant synergistic effects, further reducing required dosages and expanding application scenarios.