Qu'est-ce que Milk Thistle Extract (Silymarin/Silybin) ? Applications, dosage, alternatives et spécifications
Dernière mise à jour: 2026-11-14 · CAS 65666-07-1 · qualité alimentaire
- Fiche express
- Nom
- Milk Thistle Extract (Silymarin/Silybin)
- Numéro CAS
- 65666-07-1
- Qualité
- qualité alimentaire
- Certifications
- ISO 9001 · ISO 22000 · HACCP · FAMI-QS · Kasher · Hallal · GMP · SGS
- Domaines d'application
- 5
- Documentation
- COA · TDS · SDS
Aperçu
lait Thistle, with botanical name Silybum marianum (L.) Gaertn., est unn annual or biennial herb belonging to the Asteraceae family. lait Thistle extrait (also known as Silymarin) est un naturel plant extrait produced from the dried ripe fruits of Silybum marianum through extraition, purification, and drying processes. The main active component is Silymarin, which appears as a yellow or brown-yellow poudre or crystalline poudre with a bitter taste. Silymarin has been used to treat hepatobiliary diseases for over 2,000 years. In ancient Greece and Roman times, lait Thistle was already used to treat liver and gallbladder disorders. Modern research shows that Silymarin est reconnu comme one of the most effective flavonoids for liver diseases discovered to date, earning the title of "naturel hepatoprotective agent". Silymarin refers to a flavonolignan compound extraited from the seed coat of Silybum marianum, a medicinal plant of the Asteraceae family [10†L5-L6]. Silymarin exhibits multiple pharmacological activities and est largement utilisé in pharmaceuticals, health foods, foods, and cosmetics.
The core active component of lait Thistle extrait is Silymarin, a flavonolignan compound complex primarily consisting of four isomers: Silybin (also called Silibinin), Isosilybin, Silychristin, and Silydianin. Silybin is the most abundant and biologically active component in Silymarin, typically accounting for 50% to 70% of total Silymarin content. Active Component
(3) Promotion of Hepatocyte Regeneration and réparation: Silymarin accelerates DNA synthesis in liver cells and favorise protein synthesis, facilitating the production of new hepatocytes or the repair of already damaged ones. Clinical studies have demonstrated that Silybin stabilizes the hepatocyte membrane, maintient its integrity, favorise the restoration of hepatocellular ultrastructure, rehausse the division and growth of normal hepatocytes, and augmente the synthesis of RNA and proteins in hepatocytes.
Applications
Pharmaceuticals
lait Thistle extrait is registered and used as a pharmaceutical product in multiple countries worldwide, representing a core component of the…
santé aliments and complément alimentaires
lait Thistle extrait is the most popular core ingredient in liver health health foods worldwide.
aliment fonctionnels and boissons
aliment fonctionnels and boissons
Cosmetics and Personal Care
lait Thistle extrait is seeing rapidly growing applications in cosmetics due to its antioxydant, anti-aging, and soothing properties.
vétérinaire Medicine and aliment additifs
vétérinaire Medicine and aliment additifs
Spécification
| Specification/Teneur | Méthode d'Essai | Main Characteristics |
|---|---|---|
| Typical Applications | ||
| Silymarin (Faible) | 40%–50% | UV |
| Yellow poudre, primary processed product | General health foods, feed additives | |
| Silymarin (Moyen) | 60%–80% | UV/HPLC |
| Brown-yellow poudre, standardized | Pharmaceuticals, health foods, food ingredients | |
| Silymarin (Élevé) | 80%–90%+ | HPLC |
| Élevé-purity brown-yellow poudre | Premium health foods, UE/États-Unis exports, pharmaceuticals | |
| Silybin Monomer | 30%, 95%, 98%, 99% | HPLC |
| Poudre cristalline blanche à blanc cassé | Pharmaceutical products, premium formulations, research | |
| eau-soluble Silymarin | 20%, 40% | UV |
| Modified for water solubility | boissons, solid beverages, cosmetics | |
| Phospholipid complexe | normeized Silybin | HPLC |
| Phytosome® technology, greatly enhanced bioavailability | Premium health foods, pharmaceuticals | |
| Ratio extrait | 10:1, 20:1, 50:1 | TLC/UV |
| Retains multiple naturel active components | Functional foods, general health foods | |
| 3.3 Typical Technique Specifications | Paramètre | Specification Range/Index |
| Méthode d'Essai | ||
| Aspect | Jaune clair to brown-yellow poudre or crystalline poudre | inspection visuelle |
| Silymarin (UV) | ≥80% (standard); 40%–90% (customizable) | UV colorimetry |
| Silymarin (HPLC) | 30%–80% (customizable) | HPLC |
| Silybin (HPLC) | 30%, 50%, 95%, 98%, 99% | HPLC |
| Perte au séchage | ≤5.0% | Thermogravimetric method |
| Cendres | <5.0% | Élevé-temperature ignition |
| Plomb (Pb) | ≤1.0 mg/kg | ICP-MS/AAS |
| Arsenic (As) | ≤1.0 mg/kg | ICP-MS/AAS |
| Cadmium (Cd) | ≤0.2 mg/kg | ICP-MS/AAS |
| Mercure (Hg) | ≤0.2 mg/kg | ICP-MS/AAS |
| Pesticide Residues | Compliant with national and export target country standards | GC-MS/LC-MS/MS |
| solvant Residues | Compliant with Chinese Pharmacopoeia standards | Gas chromatography |
| Total Aerobic Microbial Count | ≤1000 CFU/g | Plate count method |
| Yeasts and Molds | ≤100 CFU/g | Plate count method |
| E. coli | Non détecté | Culture method |
| Salmonella (25g) | Non détecté | Culture method |
| Staphylococcus aureus (25g) | Non détecté | Culture method |
| Spécifications d'Emballage | 1 kg/sac, 25 kg/fût; customizable | — |
| Durée de conservation | 24–36 mois (sealed, protected from light, dry conditions) | |
| 4. Product Application Fields |
Conditionnement et stockage
- Emballage : 25kg net fût en fibre avec double doublure PE.
- Echantillon : 100-500g échantillon gratuit disponible.
- Stockage : Conserver dans un emballage hermétiquement fermé, au frais, au sec, bien ventilé. Protéger de la lumière et de l'humidité.
- Durée de conservation : 24 mois à compter de la date de production.
Qualité et certifications
Chaque lot testé par le laboratoire interne de contrôle qualité. COA, TDS, SDS fournis avec chaque expédition.
Réglementation et conformité
UE
Conforme aux réglementations de l'UE et aux normes FAMI-QS.
États-UnisA
Conforme aux exigences FDA et AAFCO.
Chine
Enregistré selon les réglementations chinoises du MOA.
international
Casher, halal, certifié ISO. Formulaires FTA disponibles.
Sécurité et manipulation
- Classe de danger : Généralement non dangereux. Consulter la SDS pour les détails.
- Stockage : Température ambiante, sec, scellé. Éviter les oxydants forts.
- transport : Marchandises non dangereuses. Fret maritime/aérien standard.
- SDS: Disponible sur demande à sales@xadditive.cn.
Questions fréquentes
Q1 : MOQ ?
La MOQ est de 1 kg pour l'essai, 25 kg pour les commandes régulières. Échantillons gratuits disponibles.
Q2 : Durée de conservation ?
24 mois à compter de la date de production dans de bonnes conditions de stockage.
Q3 : certifications ?
ISO 9001, ISO 22000, HACCP, FAMI-QS, casher, halal, COA, SDS, TDS.
Q4 : Comment obtenir un devis ?
Envoyez un e-mail à sales@xadditive.cn avec vos besoins. Réponse sous 30 minutes.
Demander un devis et un COA
Demandez la fiche technique en vigueur, un exemplaire de COA et un devis quantitatif — réponse sous 30 minutes les jours ouvrés.