Apa Itu Beta-Alanine Powder (Food/Feed/Supplement Grade)? Aplikasi, Dosis, Alternatif & Spesifikasi

Beta Alanine, chemically known as 3-Aminopropionic acid, is a naturally occurring βtype amino acid and is the only βamino acid found in nature. It is a nonproteinogenic amino acid with wide application value in global sports nutrition supplements, food additives, pharmaceutical raw materials, and cosmetics. Its molecular formula is C3H7NO2, molecular weight is 89.09, CAS number is 107–95–9, and EINECS number is 203–536–5. βAlanine is a component of pantothenic acid (vitamin B5) and is the ratelimiting precursor for the biosynthesis of the histidine-containing dipeptide carnosine. Pantothenic acid is formed by the condensation of βalanine and pantoic acid, and is further involved in the synthesis of coenzyme A, thereby affecting energy metabolism, fatty acid oxidation, and the tricarboxylic acid cycle in the body. Carnosine, which is concentrated in skeletal muscle tissue, is composed of βalanine and Lhistidine. As an intracellular pH buffer, carnosine helps athletes combat fatigue and enhance performance during intense exercise such as sprinting and weight training. βAlanine appears as white crystalline powder or colorless crystals, odorless, with a characteristic sweet taste, approximately 70% as sweet as sucrose. It starts to sublimate above 200°C, with a melting point of approximately 198°C (decomposition). It has stable chemical properties, is soluble in water (solubility approximately 17% at 25°C), slightly soluble in ethanol, and insoluble in diethyl ether. The pH of a 1% aqueous solution is approximately 5.57.0, which is neutral to slightly acidic. As a nonproteinogenic amino acid, βalanine is produced endogenously in the liver and can also be obtained from dietary sources such as chicken, fish, turkey, and beef. However, the amount of βalanine obtained from food alone is usually insufficient to significantly elevate carnosine levels, making supplementation an effective method to increase muscle carnosine concentrations.

βAlanine is widely recognized as a “highintensity performance enhancer” and is an indispensable core ingredient in modern sports nutrition and health functional products. Its most outstanding advantages lie in its role as the ratelimiting precursor for carnosine synthesis, its superior buffering capacity, and its strong scientific validation. RateLimiting Precursor for Carnosine Synthesis: βAlanine combines with histidine in the body to form carnosine. Carnosine synthesis is limited by the availability of βalanine. Supplementing with βalanine is currently the most effective known method to increase muscle carnosine concentrations. The ISSN position stand clearly states that daily supplementation with 46 g of βalanine for at least 24 weeks can significantly improve exercise performance Supplementation for 10 weeks can increase muscle carnosine concentrations by up to 80%.

Superior Intracellular pH Buffering Capacity: During highintensity exercise, the accumulation of lactic acid in muscle cells leads to a drop in pH, which is a primary cause of fatigue. Carnosine, with its imidazole ring protonbuffering characteristics, effectively neutralizes hydrogen ions, delays pH decline, and prolongs the duration of highintensity exercise. By increasing carnosine concentration, βalanine significantly delays neuromuscular fatigue and enhances exercise endurance, with the most pronounced improvements observed in highintensity exercise lasting 14 minutes.