What Is L-Histidine (Food/Feed/Cell-Culture Grade)? Applications, Dosage, Alternatives & Specifications
Last updated: 2026-11-14 · CAS 71-00-1 · Food Grade
- Quick facts
- Name
- L-Histidine (Food/Feed/Cell-Culture Grade)
- CAS number
- 71-00-1
- Grade
- Food Grade
- Certifications
- ISO 9001 · ISO 22000 · HACCP · FAMI-QS · Kosher · Halal · GMP · SGS
- Application areas
- 6
- Documentation
- COA · TDS · SDS
Overview
L-Histidine (Food/Feed/Cell-Culture Grade) is a premium-quality product supplied by ZEAL BIOTECH under strict quality management with full batch traceability, formulated for Low-protein swine diets and precision feeding and related applications.
Applications
Swine
Crystalline amino acids enable low-protein, precisely balanced diets.
Poultry
Methionine, lysine, threonine and tryptophan meet the ideal protein profile.
Aquaculture
Amino acid supplementation balances plant-protein aquafeeds.
Ruminants
Protected amino acids and precursor programs for dairy and beef.
Pet Food
Protein balancing and palatability support in pet diets.
Premix Plants
Accurate micro-ingredient weighing and blending.
Specification
| Parameter | Specification | Test Method | ||
|---|---|---|---|---|
| Color | White | Place appropriate amount of sample in a clean, dry white porcelain plate, observe under natural light | ||
| State | Crystalline powder or needle-like crystals | Same as above | ||
| Odor | Odorless, slightly bitter taste | Olfactory | ||
| Physicochemical Specifications (based on USP, FCC, AJI standards): | Parameter | USP Standard | FCC Standard | AJI Standard |
| Test Method | ||||
| L-Histidine Content (as C6H9N3O2 on dried basis), % | 98.5–101.5 | 98.5–101.5 | 99.0–101.0 | Perchloric acid non-aqueous titration / HPLC |
| Specific Optical Rotation [α]20D (c=11, 6N HCl) | +12.6°~+14.0° | +12.0°~+13.0° | +12.6°~+14.0° | Polarimeter |
| Transmittance, % | ≥98.0 | — | ≥98.0 | Spectrophotometry |
| Loss on Drying, % | ≤0.20 | ≤0.20 | ≤0.20 | Loss on drying method |
| Residue on Ignition, % | ≤0.40 | ≤0.40 | ≤0.10 | Ignition method |
| pH Value (1% aqueous solution) | 7.0–8.5 | 7.0–8.5 | 7.0–8.5 | pH meter |
| Chlorides (Cl), % | ≤0.05 | ≤0.05 | ≤0.02 | Silver nitrate precipitation turbidimetry |
| Sulfates (SO4), % | ≤0.03 | — | ≤0.02 | Barium chloride precipitation turbidimetry |
| Ammonium Salts (NH4), % | — | — | ≤0.02 | Colorimetry |
| Iron (Fe), % | ≤0.003 | — | ≤0.001 | Thiocyanate colorimetry |
| Heavy Metals (as Pb), mg/kg | ≤15 | ≤15 | ≤10 | Thioacetamide method / ICP-MS |
| Arsenic (As), mg/kg | — | — | ≤1 | Atomic fluorescence spectrometry |
| Other Amino Acids | Total impurities ≤2.0%, single ≤0.5% | — | Not detected | Thin layer chromatography / HPLC |
| Total Plate Count, CFU/g | ≤1000 | ≤1000 | ≤1000 | Microbial testing |
| Coliforms, MPN/g | — | — | ≤0.3 | Microbial testing |
| Salmonella | — | — | Not detected | Microbial testing |
| Yeast and Mold, CFU/g | ≤100 | ≤100 | ≤100 | Microbial testing |
| The above specifications are based on USP, FCC, AJI, and other international standards and supplier specifications. |
Packaging & Storage
- Packing: 25kg net fiber drum with double PE liner.
- Sample: 100-500g free sample available.
- Storage: Keep in tightly closed packaging, cool, dry, well-ventilated. Protect from light and moisture.
- Shelf Life: 24 months from production date.
Quality & Certifications
Every batch tested by in-house QC lab. COA, TDS, SDS provided with each shipment.
Regulatory & Compliance
EU
Complies with EU regulations and FAMI-QS standards.
USA
Meets FDA and AAFCO requirements.
China
Registered under Chinese MOA regulations.
International
Kosher, Halal, ISO certified. FTA forms available.
Safety & Handling
- Hazard Class: Generally non-hazardous. Refer to SDS for details.
- Storage: Room temperature, dry, sealed. Avoid strong oxidizers.
- Transport: Non-dangerous goods. Standard sea/air freight.
- SDS: Available on request at sales@xadditive.cn.
Frequently asked questions
MOQ?
MOQ is 1kg for trial, 25kg for regular orders. Free samples available.
Shelf life?
24 months from production date when stored properly.
Certifications?
ISO 9001, ISO 22000, HACCP, FAMI-QS, Kosher, Halal, COA, SDS, TDS.
How to get quote?
Email sales@xadditive.cn with your requirement. Reply within 30 minutes.
Request a quote & COA
Ask for the current specification sheet, a COA sample and a bulk quotation — reply within 30 minutes on working days.