What Is Anhydrous Calcium Citrate USP/? Applications, Dosage, Alternatives & Specifications

Calcium Citrate is an organic calcium salt composed of calcium ions and citrate ions, generally existing in the form of tetrahydrate (Calcium Citrate Tetrahydrate, Ca3(C6H5O7)2·4H2O) or anhydrous form. The tetrahydrate molecular formula is C12H10Ca3O14·4H2O with molecular weight 570.50 (anhydrous C12H10Ca3O14 molecular weight 498.43). Calcium citrate is an important intermediate in the industrial production of citric acid. When calcium hydroxide is used for neutralization during the citric acid fermentation process, insoluble calcium citrate precipitates out, which can be filtered from the liquid and washed to obtain a pure product. Calcium citrate, as a food nutrient fortifier, dietary supplement ingredient, feed additive, and pharmaceutical excipient, is widely used in calcium fortification, nutritional supplementation, pharmaceutical preparations, and animal nutrition. It is a form of calcium commonly used in dietary supplements. It is a salt of citric acid and calcium that is easily absorbed by the body. Calcium citrate is a good source of calcium, an important mineral that helps build and maintain strong bones and teeth, regulate muscle contractions, and support nerve function. Calcium citrate is often preferred over other forms of calcium due to its bioavailability and ease of digestion. Physicochemical Properties

Appearance: White crystalline powder, odorless, slightly hygroscopic, very slightly soluble in water (0.095g/100mL, 25°C), soluble in dilute acid, almost insoluble in ethanol.

Crystal Water Characteristics: Contains 4 molecules of crystal water, gradually loses crystal water when heated to 100°C, loses all crystal water when heated to 120°C.